Hara Laboratory

Tokyo Institute of Technology

School of Materials and Chemical Technology

Department of Chemical Science and Engineering


Surface and Interfacial Science, Nanotechnology and Nanosciences



Nanotechnology & Nanoscience

based on

Surface Sciences

1. Functional molecular interfaces:

     from electric nanodevices to nano-bio interfaces

2. Nanoscale Analysis of Self-Assebled Monolayers 

3. Single Molecule Optical and Force spectroscopy

4. Prebiotic Chemistry and Origins of Life

5. Nanophotonics


Masahiko Hara

Assistant Professor

Daisuke Ishikawa

Special Researcher

​Takaaki Yano


Nobue Ueda

Ph. D. student

Sebastian Sanden

Mervat Ameen

Mitsunobu Takemoto


Master Course Student

Mamoru Manabe

Fiansyah Reiza Bidari

Yuma Hiraoka

Kimika Horinouchi

Kodai Koshino

Masako Masuda

Nagi Yamashita

Takuma Hirabara

Kaito Katayama

Shunjiro Sodei

Daichi Uchida

Research Student

Zhang Chaoyi



Y. J. Son, S. Han, K. Yoshizawa, T. Hayashi, M. Hara, and J. Noh, "Displacement Processes of 1-Adamanetanethiol Self-Assembled Monolayers on Au(111) by 1-Hexanethiol"

J. Nanosci. Nanotechnol. 19, 4732–4735 (2019).

S. Han, H. Park, J. W. Han, K. Yoshizawa, T. Hayashi, M. Hara, and J. Noh, "Solvent Effect on the Formation of Octaneselenocyanate Self-Assembled Monolayers on Au(111)"

J. Nanosci. Nanotechnol. 19, 4795–4798 (2019).

Y. Choi, S. Seong, Y. J. Son, S. Han, E. Ito, E. A. Q. Mondarte, R. Chang, T. Hayashi, M. Hara, and J. Noh, "Formation of long-range-ordered self-assembled monolayers of dodecyl thiocyanates on Au(111) via ambient-pressure vapor deposition"

Colloid Surface A 583, 123969 (2019).

G. Barcaro, L. Sementa, V. Carravetta, T. Yano, M. Hara, and S. Monti, "Experimental and theoretical elucidation of catalytic pathways in TiO2-initiated prebiotic polymerization"

Phys. Chem. Chem. Phys. 21, 5435–5447 (2019).

T. Yano and M. Hara,"Tip-enhanced Raman scattering microscopy: A step toward nanoscale control of intrinsic molecular properties"

J. Phys. Soc. Jpn. 87, 061012 (2018).

T. Suzuki, T. Yano, M. Hara, and T. Ebisuzaki, "Cysteine and cystine adsorption on FeS2(100)"

Surf. Sci. 674, 6-12 (2018).

R. Afrin, N. Ganbaatar, M. Aono, H.J. Cleaves, T. Yano, and M. Hara, “Size-dependent affinity of glycine and its short oligomers to pyrite surface: a model for prebiotic accumulation of amino acid oligomers on a mineral surface“

Int. J. Mol. Sci. 19, 365 (2018).

K. Suzuki, D. Kato, K. Hara, T. Yano, M. Hirayama, H. Masahiko, and R. Kanno, 

“Composite Sulfur Electrode for All-Solid-State Lithium-Sulfur Battery with Li2S-GeS2-P2S5-Based Thio-LISICON Solid Electrolyte” 

Electrochemistry, 86, 1-5 (2018).

T. Sung, S. Seong, S. Han, Y.J. Son, T. Ishida, T. Hayashi, M. Hara, and J. Noh, “Well-Ordered Domains of 4-Fluorobenzenethiol Self-Assembled Monolayers on Au(111) Guided by a Displacement Reaction“

J. Nanosci. Nanotechnol. 18, 7053–7057 (2018).

N. Ganbaatar, K. Imai, T. Yano, and M. Hara “Surface force analysis of glycine adsorption on different crystal surfaces of titanium dioxide (TiO2)”

Nano Convergence 4, 38 (2017).

K. Hara, T. Yano, J. Hata, K. Hikima, K. Suzuki, M. Hirayama, R. Kanno, and M. Hara, “Nanoscale optical imaging of lithium-ion distribution on a LiCoO2 cathode surface”

Appl. Phys. Express 10, 052503 (2017).

K. Suzuki, D. Kato, K. Hara, T. Yano, M. Hirayama, M. Hara, and R. Kanno, “Composite Sulfur Electrode Prepared by High-Temperature Mechanical Milling for use in an All-Solid-State Lithium-Sulfur Battery with a Li3.25Ge0.25P0.75S4 Electrolyte“

Electrochimica Acta 258, 110−115 (2017).

H. Kang , S. Han , S. Seong , Y. Son , E. Ito, M. Hara, and J. Noh, “Unique Mixed Phases and Structures of Self-Assembled Monolayers on Au(111) Derived from Methoxy-terminated Mono(ethylene glycol)ethanethiols

J. Phys. Chem. C 121, 18021-18029 (2017).

K. Hara, T. Yano, K. Suzuki, M. Hirayama, T. Hayashi, R. Kanno, and M. Hara, “Raman imaging analysis of local crystal structures in LiCoO2 thin films calcined at different temperature”

Anal. Sci. 33, 853-858 (2017).

A. Portela, T. Yano, C. Santschi, O.J.F. Martin, H. Tabata, and M. Hara, "Highly sensitive SERS analysis of the cyclic Arg-Gly-Asp peptide ligands of cells using nanogap antennas" 

J. Biophoton. 10, 294-302 (2017).

M. Han, K. Ku, H. Kang, R. Ohashi, T. Hayashi, M. Hara, and J. Noh, “Standing-Up Phase of Hexanedithiol Self-Assembled Monolayers on Au(111) Induced by Displacement Reaction”

J. Nanosci. Nanotechnol. 17, 5780–5783 (2017).

Z. Quan, M. Hirayama, D. Sato, Y. Zheng, T. Yano, K. Hara, K. Suzuki, M. Hara, and R. Kanno, “Effect of Excess Li2S on Electrochemical Properties of Amorphous Li3PS4 Films Synthesized by Pulsed Laser Deposition” 

J. Am. Ceram. Soc. 100, 746-753 (2017).

T. Yano*, Y. Tsuchimoto, R. P. Zaccaria, A. Toma, A. Portela, and M. Hara, “Enhanced optical magnetism for reversed optical binding forces between silicon nanoparticles in the visible region” 

Optics Express 25, 431-439 (2017).

S. Seong, H. Kang, S. Han, T. Sung, J. B. Park, T. Hayashi, M. Hara, and J. Noh “Formation and Structural Changes of 4-Fluorobenzenethiol Self-Assembled Monolayers on Au(111)”

J. Nanosci. Nanotech. 17, 5597-5600 (2017).


G. Narangerel, N. Matsuzaki, Y. Nakazawa, R. Afrin, M. Aono, T. Yano, T. Hayashi, and M. Hara, "Surface force analysis of pyrite (FeS2): its reactivity to amino acid adsorption"

Adv. Mater. Phys. Chem. 6, 167-176 (2016).

H. Wang, H. Y. Wang, A. Toma, T. Yano, Q. D. Chen, H.L. Xu, H. B. Sun, and R. P. Zaccaria, “Dynamics of Strong Coupling between CdSe Quantum Dots and Surface Plasmon Polaritons in Subwavelength Hole Array”

J. Phys. Chem. Lett. 7, 4648-4654 (2016).

Y. Tsuchimoto, T. Yano, T. Hayashi, and M. Hara, “Fano resonant all-dielectric core/shell nanoparticles with ultrahigh scattering directionality in the visible region,”

Optics Express 24, 14451-14462 (2016).

Y. Sun, K. Suzuki, K. Hara, S. Hori, T. Yano, M. Hara, M. Hirayama, and R. Kanno, “Oxygen substitution effects in Li10GeP2S12 solid electrolyte”

J. Power Sources 324, 798-803 (2016).

T. Yano, Y. Tsuchimoto, M. Mochizuki, T. Hayashi, and M. Hara, "Laser Scanning Assisted Tip-Enhanced Optical Microscopy for Robust Optical Nanospectroscopy,"

Appl. Spectrosc. 70, 1239–1243 (2016).

K. Sunamura, T. R. Page, K. Yoshida, T. Yano, and Y. Hayamizu, "Laser-induced electrochemical thinning of MoS2"

J. Mater. Chem. C, 4, 3268-3273 (2016).

K. Iwayama, Y. Hirata,  M. Aono, L. Zhu, M. Hara, and K. Aihara, "Decision-making ability of Physarum polycephalum enhanced by its coordinated spatiotemporal oscillatory dynamics," 

Bioinspiration & Biomimetics 11, 036001 (2016).

H. Kang, E. Ito, M. Hara, and J. Noh, "Formation of Ordered 4-Fluorobenzenethiol Self- Assembled Monolayers on Au(111) from Vapor Phase Deposition, "

J. Nanosci. Nanotech. 16, 2800-2803, (2016).

Y. Kim, H. Kang, T. Hayashi, M. Hara, and J. Noh, "Striped Phase of 3- Hexylthiophene Self-Assembled Monolayers on Au(111) Formed by Vapor Phase Deposition,"

J. Nanosci. Nanotech. 16, 2792-2795, (2016).

H. Jeong, H. Kang, S. Han, H. Park, J. Han, T. Hayashi, M. Hara, and J. Noh, "Comparative Study for Displacement of Cyclohexanethiolate and Cyclohaxaneselenolate Self- Assembled Monolayers on Au(111) by Octanethiol,"

J. Nanosci. Nanotech. 16, 8505-8512 (2016).

S. Han, H. Kang, J. B. Park, T. Hayashi, M. Hara, and J. Noh, "Formation and Structure of Self-Assembled Monolayers by Adsorption of Octaneselenocyanate on Au(111),”

J. Nanosci. Nanotech 16, 8610-8613 (2016).

H. Kang, E. Ito, T. Hayashi, M. Hara, and J. Noh, "Effect of Solution Concentration on the Formation of Ordered Domains in Pentachlorobenzenethiol Self-Assembled Monolayers on Au(111),"

J. Nanosci. Nanotech. 16, 6360-6363 (2016).



A collection of analytical tools we've utilized for surface sciences

UHV Evaporator
UHV Evaporator
Thermal Desorption Spectroscopy(TDS)
Atomic Force Microscope (AFM)
Scanning Tunneling Microscope (STM)
Vacuum Evaporator
Dynamic Light Scattering (DLS)
Surface Plasmon Resonance (SPR)
Surface-Enhanced Raman scattering (S


4259 Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8502 Japan.

Suzukakedai Campus, G1 bldg.
Room#1008(Prof. Masahiko Hara)

Room#1005(Assist. Prof. Daisuke Ishikawa)

E-mail: haralab@echem.titech.ac.jp

Tel: +81-45-924-5437

Thermal Desorption Spectroscopy(TDS)